Recurrent Corneal Perforation and Acute Calcareous Corneal Degeneration in Chronic Graft-Versus-Host Disease
نویسندگان
چکیده
منابع مشابه
Recurrent Corneal Perforation due to Chronic Graft versus Host Disease; a Clinicopathologic Report
PURPOSE To describe a case of chronic graft versus host disease (GVHD) leading to severe dry eye and recurrent corneal perforation in both eyes, its stepwise management and histopathological reports. CASE REPORT A 22-year-old woman with a history of thalassemia and subsequent high-dose chemotherapy followed by allogeneic bone marrow transplant (BMT) was referred to Farabi Eye Hospital. Despit...
متن کاملFour cases of corneal perforation in patients with chronic graft-versus-host disease
PURPOSE To report the clinical features and investigate the underlying pathological processes of spontaneous corneal perforation in patients with ocular chronic graft-versus-host disease (cGVHD). METHODS A full ophthalmological evaluation of corneal perforation in four patients with cGVHD was performed. Three of them underwent deep anterior lamellar keratoplasty and samples from two of three ...
متن کاملBilateral corneal ulceration in ocular graft-versus-host disease
PURPOSE To report on corneal ulceration in ocular graft-versus-host disease (GVHD). METHODS This was a retrospective, observational case series investigating corneal ulceration and perforation in a cohort of ocular GVHD patients seen between June 2007 and October 2012. RESULTS Four of 243 ocular GVHD patients developed corneal ulcerations attributable to ocular GVHD, and all four cases invo...
متن کاملProgressive corneal vascularization caused by graft-versus-host disease.
PURPOSE To report a case with severe dry eye and progressive corneal vascularization caused by graft-versus-host disease (GVHD). METHODS A case report and review of literature. RESULTS A 50-year-old man with history of acute myeloblastic leukemia, high-dose chemotherapy for eradication of hematopoietic stem cells, subsequent allogenic bone marrow transplantation, and eventually GVHD was ref...
متن کاملDeep lamellar keratoplasty for corneal perforation due to chronic graft-versus-host disease following allogeneic hematopoietic stem-cell transplantation.
Chronic graft-versus-host disease (GVHD) is a common complication following allogeneic hematopoietic stem-cell transplantation (alloHSCT), frequently involving the ocular system. Topical or systemic use of corticosteroid is occasionally beneficial; however, there has been cases to progress to corneal perforation. We will report a case of a patient who developed corneal perforation in the course...
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ژورنال
عنوان ژورنال: Journal of the Formosan Medical Association
سال: 2006
ISSN: 0929-6646
DOI: 10.1016/s0929-6646(09)60125-x